What is a common ocular consequence of prolonged contact lens wear?

Prolonged contact lens wear is associated with corneal neovascularization, which refers to the growth of new blood vessels into the cornea. This condition arises because contact lenses can lead to hypoxia (reduced oxygen supply) to the corneal tissues, especially if the lenses are worn for extended periods, including overnight. The cornea relies heavily on oxygen from the air, as it does not have its own blood supply. When oxygen levels drop due to contact lens wear, the cornea attempts to compensate by initiating neovascularization, allowing new blood vessels to grow from the limbal region into the cornea to supply necessary nutrients and oxygen.

While conjunctival hyperemia is indeed a common finding in those with prolonged lens wear, it is typically a more superficial response and does not denote the more serious underlying issue of corneal tissue hypoxia leading to neovascularization. Other options like reactive hyperplasia of corneal endothelium and subconjunctival hemorrhage are less directly related to the primary consequences of contact lens wear and are not as prevalent in this specific context. Thus, corneal neovascularization stands out as a significant ocular consequence specifically linked to the effects of extended contact lens use.